Brachydactyly type B1

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Brachydactyly type B1

ORPHA:572385Clinical subtype

What it is

A rare subtype of brachydactyly type B characterized by hypoplasia or aplasia of the distal phalanges of digits 2-5 with or without nail dysplasia, in association with fusion of the middle and distal phalanges, a broad or bifid thumb, and occasionally distal and proximal symphalangism or syndactyly. The feet are less severely affected than the hands.

Key facts

Prevalence
<1 / 1 000 000
Age of onset
Antenatal
Inheritance
Autosomal dominant
Classified as
Clinical subtype

Prevalence figures describe populations, not individuals, and are often estimates from a single study. Where the figure is an incidence or a birth prevalence, it says so.

Gene

ROR2Disease-causing germline mutation(s) (gain of function)

ICD-10 codes

Q73.8filed under a broader ICD-10 category — shared with 25 other rare diseases

ICD-10 has no distinct code for most rare diseases, so many are filed under the nearest available one. A shared code identifies the group, not this disease — the ORPHAcode above is what identifies it.

Cross-references

MESH C566196MONDO 0007220OMIM 113000UMLS C1862112

Orphadata Science: Free access data from Orphanet. © INSERM 1999. Data version 2026-06-23. Available under CC BY 4.0. This is a reference, not medical advice.

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