Amniotic fluid embolism

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Amniotic fluid embolism

ORPHA:617304Disease

What it is

A rare obstetric condition characterized by entry of amniotic fluid and fetal elements into the maternal circulation, causing an emergency situation with sudden cardiovascular collapse, disseminated intravascular coagulation, and high lethality. In most instances it occurs during labor, cesarean delivery, or within 30 minutes postpartum. Patients present acute dyspnea and cough, acute hypotension, encephalopathy with altered mental status and seizures, hypoxia and cyanosis, coagulopathy, severe hemorrhage, uterine atony, acute pulmonary hypertension, and cardiac arrest.

Key facts

Age of onset
Adult
Inheritance
Not applicable
Classified as
Disease

ICD-10 codes

O88.1ICD-10 names this disease exactly

Cross-references

MESH D004619MONDO 0850046UMLS C0013927

Orphadata Science: Free access data from Orphanet. © INSERM 1999. Data version 2026-06-23. Available under CC BY 4.0. This is a reference, not medical advice.

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