Adenocarcinoma of the penis

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Adenocarcinoma of the penis

ORPHA:398053Disease

Also called Penile adenocarcinoma

What it is

An extremely rare penile epithelial neoplasm, histologically composed of nests of epithelilal cells floating in lakes of extracellular, PAS-positive mucin, clinically characterized by a nonhealing ulcer or soft mass in the preputium or glans area, with itching and burning often preceding appearance of the lesion. Lymphadenopathy may indicate dissemination. Mucinous metaplasia of the penis may be a risk factor.

Key facts

Prevalence
<1 / 1 000 000 (annual incidence, Europe)
Age of onset
Elderly
Inheritance
Not applicable
Classified as
Disease

Prevalence figures describe populations, not individuals, and are often estimates from a single study. Where the figure is an incidence or a birth prevalence, it says so.

ICD-10 codes

C60.0filed under a broader ICD-10 category — shared with 1 other rare disease
C60.1filed under a broader ICD-10 category — shared with 1 other rare disease
C60.2filed under a broader ICD-10 category — shared with 1 other rare disease
C60.8filed under a broader ICD-10 category — shared with 1 other rare disease
C60.9filed under a broader ICD-10 category — shared with 1 other rare disease

ICD-10 has no distinct code for most rare diseases, so many are filed under the nearest available one. A shared code identifies the group, not this disease — the ORPHAcode above is what identifies it.

Cross-references

UMLS C2212153

Orphadata Science: Free access data from Orphanet. © INSERM 1999. Data version 2026-06-23. Available under CC BY 4.0. This is a reference, not medical advice.

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