Undifferentiated carcinoma

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Undifferentiated carcinoma with osteoclast-like giant cells of pancreas

ORPHA:424080Disease

Also called OGCT of pancreas · Osteoclastic giant cell tumor of pancreas · Pancreatic osteoclastic giant cell tumor · Pancreatic undifferentiated carcinoma with osteoclast-like giant cells · Undifferentiated carcinoma of pancreas with osteoclast-like giant cells

What it is

A rare type of pancreatic ductal adenocarcinoma characterized by composition of non-neoplastic osteoclast-like multinucleated giant cells, a mononuclear histiocytic component, and the neoplastic cells, which vary from spindle-shaped to epithelioid and can be very large and pleomorphic. Clinical features of pancreatic ductal adenocarcinoma include abdominal pain, nausea, weight loss, jaundice, and new-onset diabetes.

Key facts

Prevalence
<1 / 1 000 000 (annual incidence, Europe)
Age of onset
Adult
Inheritance
Not applicable
Classified as
Disease

Prevalence figures describe populations, not individuals, and are often estimates from a single study. Where the figure is an incidence or a birth prevalence, it says so.

ICD-10 codes

C25.0ICD-10 uses a narrower term — shared with 5 other rare diseases
C25.1ICD-10 uses a narrower term — shared with 6 other rare diseases
C25.2ICD-10 uses a narrower term — shared with 5 other rare diseases
C25.7ICD-10 uses a narrower term — shared with 5 other rare diseases
C25.8ICD-10 uses a narrower term — shared with 5 other rare diseases

ICD-10 has no distinct code for most rare diseases, so many are filed under the nearest available one. A shared code identifies the group, not this disease — the ORPHAcode above is what identifies it.

Related health topics

Reached through the ICD-10 categories this disease is filed under, so these describe the broader group rather than this disease specifically.

Cross-references

MONDO 0006479UMLS C2007059

Orphadata Science: Free access data from Orphanet. © INSERM 1999. Data version 2026-06-23. Available under CC BY 4.0. This is a reference, not medical advice.

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