Tropical spastic paraparesis

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Tropical spastic paraparesis

ORPHA:289326Disease

Also called HAM/TSP · HTLV-1-associated myelopathy/tropical spastic paraparesis · Human T-lymphotropic virus type I-associated myelopathy/tropical spastic paraparesis · Human T-lymphotropic virus type-1-associated myelopathy/tropical spastic paraparesis · TSP

What it is

Tropical spastic paraparesis is a chronic systemic immune-mediated inflammatory myeloneuropathy, more frequently reported in women than in men, that usually presents in adulthood with slowly progressive spastic paraparesis of the lower limbs, bladder and bowel dysfunction, and sensory disturbances in the lower extremities (e.g. paresthesia and dysesthesia) and that is associated with a human T-cell lymphotropic virus type 1 (HTLV-1) infection.

Key facts

Age of onset
Adult
Inheritance
Not applicable
Classified as
Disease

ICD-10 codes

G04.1ICD-10 names this disease exactly

Related health topics

Reached through the ICD-10 categories this disease is filed under, so these describe the broader group rather than this disease specifically.

Cross-references

GARD 8208MEDDRA 10044696MESH D015493MONDO 0008039OMIM 159580UMLS C0030481

Orphadata Science: Free access data from Orphanet. © INSERM 1999. Data version 2026-06-23. Available under CC BY 4.0. This is a reference, not medical advice.

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