Rare diseases · Sign or symptom
Weak voice
Soft voice
HP:0001621
What it means
Reduced intensity (volume) of speech.
Hypophonia refers to an abnormally weak voice due to incoordination of the muscles concerned in vocalization.
Rare diseases that can present with this11
Common30–79%
6Sometimes5–29%
4The range is how often this sign appears among people diagnosed with each disease — it is not a probability of having any of them. Many of these signs also occur in common, non-rare conditions. A sign on this page is a conversation to have with a clinician, not a conclusion.
Part of the broader category
Also called: Hypophonia · Quiet voice
Tracking symptoms like this for someone? Eleplan keeps symptoms, diagnoses, medications and every specialist in one plan.
Start free with EleplanThis page uses the Human Phenotype Ontology (2026-06-23) — Human Phenotype Ontology Consortium, hpo.jax.org. Disease associations from Orphanet (INSERM), CC BY 4.0. Content is educational and is not medical advice.