Rare diseases · Sign or symptom
Toe syndactyly
Fused toes
HP:0001770
What it means
Webbing or fusion of the toes, involving soft parts only or including bone structure. Bony fusions are referred to as "bony" Syndactyly if the fusion occurs in a radio-ulnar axis. Fusions of bones of the toes in a proximo-distal axis are referred to as "Symphalangism".
Rare diseases that can present with this93
Very common80–99%
20- ADULT syndrome
- Apert syndrome
- Autosomal dominant popliteal pterygium syndrome
- Bartsocas-Papas syndrome
- Brachydactyly-syndactyly, Zhao type
- Cleft lip/palate-ectodermal dysplasia syndrome
- Cornelia de Lange syndrome
- Developmental delay-language impairment-dopa responsive dystonia-parkinsonism syndrome due to 2q24 microdeletion
- Feingold syndrome type 1
- Intellectual disability-polydactyly-uncombable hair syndrome
- Jackson-Weiss syndrome
- Laurin-Sandrow syndrome
- Megalencephaly-capillary malformation-polymicrogyria syndrome
- Mesoaxial synostotic syndactyly with phalangeal reduction
- Microphthalmia with limb anomalies
- Oculodentodigital dysplasia
- Syndactyly-telecanthus-anogenital and renal malformations syndrome
- Syndactyly type 1
- Visceral neuropathy-brain anomalies-facial dysmorphism-developmental delay syndrome
- X small rings syndrome
Common30–79%
34- 14q11.2microdeletion syndrome
- 16p11.2p12.2microdeletion syndrome
- 17q21.31microduplication syndrome
- 19q13.11microdeletion syndrome
- 2q31.1microdeletion syndrome
- 2q37microdeletion syndrome
- Aphalangy-hemivertebrae-urogenital-intestinal dysgenesis syndrome
- Aphalangy-syndactyly-microcephaly syndrome
- Camptobrachydactyly
- Camptodactyly syndrome, Guadalajara type 1
- Cenani-Lenz syndrome
- Crane-Heise syndrome
- Craniosynostosis-hydrocephalus-Arnold-Chiari malformation type I-radioulnar synostosis syndrome
- Curry-Jones syndrome
- Deafness-genital anomalies-metacarpal and metatarsal synostosis syndrome
- Feingold syndrome
- Feingold syndrome type 2
- Fraser syndrome
- Greig cephalopolysyndactyly syndrome
- Jacobsen syndrome
- Juberg-Hayward syndrome
- Lathosterolosis
- Microduplication Xp11.22p11.23 syndrome
- Pallister-Hall syndrome
- Patterson-Stevenson-Fontaine syndrome
- Peters plus syndrome
- Pfeiffer syndrome type 1
- Pfeiffer syndrome type 2
- Pfeiffer syndrome type 3
- Simpson-Golabi-Behmel syndrome
- Smith-Magenis syndrome
- Symphalangism with multiple anomalies of hands and feet
- Syndactyly type 4
- Urban-Rogers-Meyer syndrome
The range is how often this sign appears among people diagnosed with each disease — it is not a probability of having any of them. Many of these signs also occur in common, non-rare conditions. A sign on this page is a conversation to have with a clinician, not a conclusion.
Part of the broader category
Also called: Foot syndactyly · Syndactyly of feet · Syndactyly of toes · Webbed toes
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Start free with EleplanThis page uses the Human Phenotype Ontology (2026-06-23) — Human Phenotype Ontology Consortium, hpo.jax.org. Disease associations from Orphanet (INSERM), CC BY 4.0. Content is educational and is not medical advice.