Rare diseases · Sign or symptom
Renal hypoplasia
Small kidneys
HP:0000089
What it means
Hypoplasia of the kidney.
Oligomeganephronic renal hypoplasia differs from simple hypoplasia, in which the renal mass is reduced but the number of nephrons is normal.
Rare diseases that can present with this32
Very common80–99%
3Common30–79%
10- 22q11.2deletion syndrome
- Brain malformation-congenital heart disease-postaxial polydactyly syndrome
- Cerebrofacioarticular syndrome
- Deafness-intellectual disability syndrome, Martin-Probst type
- Distal limb deficiencies-micrognathia syndrome
- Poland syndrome
- Renal coloboma syndrome
- Senior-Boichis syndrome
- Short rib-polydactyly syndrome, Verma-Naumoff type
- Ulbright-Hodes syndrome
The range is how often this sign appears among people diagnosed with each disease — it is not a probability of having any of them. Many of these signs also occur in common, non-rare conditions. A sign on this page is a conversation to have with a clinician, not a conclusion.
Part of the broader category
Also called: Hypoplastic kidney · Hypoplastic kidneys · Underdeveloped kidneys
Tracking symptoms like this for someone? Eleplan keeps symptoms, diagnoses, medications and every specialist in one plan.
Start free with EleplanThis page uses the Human Phenotype Ontology (2026-06-23) — Human Phenotype Ontology Consortium, hpo.jax.org. Disease associations from Orphanet (INSERM), CC BY 4.0. Content is educational and is not medical advice.