Rare diseases · Sign or symptom
Premature closure of fontanelles
HP:0005458
What it means
Normally, the posterior and lateral fontanelles are obliterated by about six months after birth, the anterior fontanelle closes by about the middle of the second year. This term refers to the situation in which the fontanelles close at an inappropriately early time point.
Rare diseases that can present with this1
The range is how often this sign appears among people diagnosed with each disease — it is not a probability of having any of them. Many of these signs also occur in common, non-rare conditions. A sign on this page is a conversation to have with a clinician, not a conclusion.
Part of the broader category
Also called: Early closure of the bregma sutures · Early closure of the cranial sutures · Early closure of the fontanelles · Obliterated fontanelles · Premature closure of the bregma sutures · Premature closure of the cranial sutures · Premature fontanel closure
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Start free with EleplanThis page uses the Human Phenotype Ontology (2026-06-23) — Human Phenotype Ontology Consortium, hpo.jax.org. Disease associations from Orphanet (INSERM), CC BY 4.0. Content is educational and is not medical advice.