Rare diseases · Sign or symptom

Portal inflammation

HP:0033196

What it means

Infiltration of portal fields by inflammatory cells.

In nonalcoholic fatty liver disease, portal inflammation is comprised of cells referred to as chronic, i.e. lymphocytes, plasma cells, occasional eosinophils, monocytes.

Rare diseases that can present with this1

Sometimes5–29%

1

The range is how often this sign appears among people diagnosed with each disease — it is not a probability of having any of them. Many of these signs also occur in common, non-rare conditions. A sign on this page is a conversation to have with a clinician, not a conclusion.

Part of the broader category

Also called: Hepatic portal inflammation

Portal inflammation

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This page uses the Human Phenotype Ontology (2026-06-23) — Human Phenotype Ontology Consortium, hpo.jax.org. Disease associations from Orphanet (INSERM), CC BY 4.0. Content is educational and is not medical advice.