Rare diseases · Sign or symptom

Pill-rolling tremor

HP:0025387

What it means

A type of resting tremor characterized by simultaneous rubbing movements of thumb and index fingers against each other.

The name pill rolling derives from the movements that pharmacists made in earlier times when making pills by rolling them together.

Rare diseases that can present with this2

The range is how often this sign appears among people diagnosed with each disease — it is not a probability of having any of them. Many of these signs also occur in common, non-rare conditions. A sign on this page is a conversation to have with a clinician, not a conclusion.

Part of the broader category

Also called: Pill rolling

Pill-rolling tremor

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This page uses the Human Phenotype Ontology (2026-06-23) — Human Phenotype Ontology Consortium, hpo.jax.org. Disease associations from Orphanet (INSERM), CC BY 4.0. Content is educational and is not medical advice.