Perioral hyperpigmentation

What it means

Increased pigmentation, either focal or generalized, of the skin surrounding the vermilion of the lips.

Periorbital hyperpigmentation may be accompanied by Lip freckles, but this should be assessed separately.

Rare diseases that can present with this1

The range is how often this sign appears among people diagnosed with each disease — it is not a probability of having any of them. Many of these signs also occur in common, non-rare conditions. A sign on this page is a conversation to have with a clinician, not a conclusion.

Part of the broader category

Also called: Increased pigmentation around the mouth