Rare diseases · Sign or symptom
Periapical bone loss
Dark spot around tooth root on x-ray
HP:0000700
What it means
Radiolucency (reflecting a reduction in the bony substance) around the apex (the tip of the dental root).
Periapical radiolucencies can be seen with periapical granuloma, cysts, ameloblastoma, odotogenic keratatoycsts, and other lesions.
Rare diseases that can present with this1
The range is how often this sign appears among people diagnosed with each disease — it is not a probability of having any of them. Many of these signs also occur in common, non-rare conditions. A sign on this page is a conversation to have with a clinician, not a conclusion.
Part of the broader category
Also called: Bone loss around tooth root · Periapical cyst · Periapical granuloma · Periapical lesion · Periapical radiolucencies · Periapical radiolucency
Tracking symptoms like this for someone? Eleplan keeps symptoms, diagnoses, medications and every specialist in one plan.
Start free with EleplanThis page uses the Human Phenotype Ontology (2026-06-23) — Human Phenotype Ontology Consortium, hpo.jax.org. Disease associations from Orphanet (INSERM), CC BY 4.0. Content is educational and is not medical advice.