Rare diseases · Sign or symptom
Nephropathy
HP:0000112
What it means
A nonspecific term referring to disease or damage of the kidneys.
In everyday care
Most people with this sign do not have a rare disease — it appears in common conditions far more often. These general reference pages cover the same topic:
Rare diseases that can present with this50
Very common80–99%
17- AA amyloidosis
- AH amyloidosis
- ATTRV30M amyloidosis
- Cystinosis
- Dahlberg-Borer-Newcomer syndrome
- Denys-Drash syndrome
- Enamel-renal syndrome
- Galloway-Mowat syndrome
- Hereditary amyloidosis with primary renal involvement
- Indomethacin embryofetopathy
- Joubert syndrome with oculorenal defect
- Joubert syndrome with renal defect
- Lowe-Kohn-Cohen syndrome
- Primary hypomagnesemia with hypercalciuria and nephrocalcinosis with severe ocular involvement
- Schimke immuno-osseous dysplasia
- Sialidosis type 2
- Spastic paraplegia-nephritis-deafness syndrome
Common30–79%
15- Atherosclerosis-deafness-diabetes-epilepsy-nephropathy syndrome
- Beckwith-Wiedemann syndrome
- Fabry disease
- Hereditary ATTR amyloidosis
- Hyperprolinemia type 1
- Hypoxanthine guanine phosphoribosyltransferase partial deficiency
- Joubert syndrome with hepatic defect
- Liddle syndrome
- Muckle-Wells syndrome
- Multicentric carpo-tarsal osteolysis with or without nephropathy
- Multiple myeloma
- MYH9-related syndromic thrombocytopenia
- Retinal vasculopathy with cerebral leukoencephalopathy and systemic manifestations
- Wolfram syndrome
- X-linked Alport syndrome-diffuse leiomyomatosis
The range is how often this sign appears among people diagnosed with each disease — it is not a probability of having any of them. Many of these signs also occur in common, non-rare conditions. A sign on this page is a conversation to have with a clinician, not a conclusion.
Part of the broader category
Also called: Kidney damage · Kidney disease
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Start free with EleplanThis page uses the Human Phenotype Ontology (2026-06-23) — Human Phenotype Ontology Consortium, hpo.jax.org. Disease associations from Orphanet (INSERM), CC BY 4.0. Content is educational and is not medical advice.