Rare diseases · Sign or symptom

Motor impersistence

HP:0040200

What it means

The inability to maintain postures or positions (such as keeping eyes closed, protruding the tongue, maintaining conjugate gaze steadily in a fixed direction, or making a prolonged 'ah' sound) without repeated prompts.

Damage to premotor and prefrontal regions results in motor-intentional disorders that disrupt initiation, maintenance, and termination of volitional movements. Motor impersistence (i.e., failure to maintain movement) more frequently develops following right than left hemisphere lesions. {xref="PMID:17353476", xref="DOI:10.1007/978-0-387-79948-3_2046", xref="https://orcid.org/0000-0002-0736-9199"}

Part of the broader category

Also called: Negative chorea

Motor impersistence

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This page uses the Human Phenotype Ontology (2026-06-23) — Human Phenotype Ontology Consortium, hpo.jax.org. Disease associations from Orphanet (INSERM), CC BY 4.0. Content is educational and is not medical advice.