Rare diseases · Sign or symptom
Lamina lucida cleavage
HP:0003341
What it means
The formation of bullae (blisters) with cleavage in the lamina lucida layer of the skin.
Cleavage within the lamina lucida is observed in junctional epidermolysis bullosa.
Rare diseases that can present with this7
Very common80–99%
3Common30–79%
3The range is how often this sign appears among people diagnosed with each disease — it is not a probability of having any of them. Many of these signs also occur in common, non-rare conditions. A sign on this page is a conversation to have with a clinician, not a conclusion.
Part of the broader category
Also called: Blistering with junctional split · Junctional split · Subepidermal blistering with cleavage in the lamina lucida
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Start free with EleplanThis page uses the Human Phenotype Ontology (2026-06-23) — Human Phenotype Ontology Consortium, hpo.jax.org. Disease associations from Orphanet (INSERM), CC BY 4.0. Content is educational and is not medical advice.