Rare diseases · Sign or symptom

Increased circulating immature neutrophil count

HP:0032236

What it means

An abnormally increased number of immature neutrophils in the peripheral blood circulation.

Various forms of immature neutrophils appear during granulopoiesis in the bone marrow. A seven day mitotic stage (myeloblast to promyelocyte to myelocyte) is followed by a seven day maturation stage (myelocyte to metamyelocyte to band cell to mature segmented neutrophil). Mature neutrophils are normally held in storage pools in the bone marrow before their entry into the circulation.

Part of the broader category

Abnormal granulocyte count
Increased circulating immature neutrophil…

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This page uses the Human Phenotype Ontology (2026-06-23) — Human Phenotype Ontology Consortium, hpo.jax.org. Disease associations from Orphanet (INSERM), CC BY 4.0. Content is educational and is not medical advice.