Rare diseases · Sign or symptom

Generalized clonic seizure

HP:0011169

What it means

Generalized clonic seizure is a type of generalized motor seizure characterized by sustained bilateral jerking, either symmetric or asymmetric, that is regularly repetitive and involves the same muscle groups.

Generalized clonic seizures are much less common than are tonic-clonic seizures, usually occur in infants, and should be distinguished from jitteriness or shuddering attacks.

Rare diseases that can present with this8

The range is how often this sign appears among people diagnosed with each disease — it is not a probability of having any of them. Many of these signs also occur in common, non-rare conditions. A sign on this page is a conversation to have with a clinician, not a conclusion.

Part of the broader category

Also called: Generalised clonic seizure · Generalised clonic seizures · Generalised onset clonic seizure · Generalised-onset clonic seizure · Generalized clonic seizures · Generalized onset clonic seizure · Generalized-onset clonic seizure

Generalized clonic seizure

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This page uses the Human Phenotype Ontology (2026-06-23) — Human Phenotype Ontology Consortium, hpo.jax.org. Disease associations from Orphanet (INSERM), CC BY 4.0. Content is educational and is not medical advice.