Rare diseases · Sign or symptom
Generalized bone demineralization
HP:0006462
What it means
A generalized decrease in bone mineral density.
The terms Osteopenia or Osteoporosis should be preferred to this term, which may be obsoleted in the future.
Rare diseases that can present with this5
Common30–79%
2The range is how often this sign appears among people diagnosed with each disease — it is not a probability of having any of them. Many of these signs also occur in common, non-rare conditions. A sign on this page is a conversation to have with a clinician, not a conclusion.
Part of the broader category
Also called: Generalised bone demineralization
Tracking symptoms like this for someone? Eleplan keeps symptoms, diagnoses, medications and every specialist in one plan.
Start free with EleplanThis page uses the Human Phenotype Ontology (2026-06-23) — Human Phenotype Ontology Consortium, hpo.jax.org. Disease associations from Orphanet (INSERM), CC BY 4.0. Content is educational and is not medical advice.