Rare diseases · Sign or symptom

Generalized bone demineralization

HP:0006462

What it means

A generalized decrease in bone mineral density.

The terms Osteopenia or Osteoporosis should be preferred to this term, which may be obsoleted in the future.

Rare diseases that can present with this5

The range is how often this sign appears among people diagnosed with each disease — it is not a probability of having any of them. Many of these signs also occur in common, non-rare conditions. A sign on this page is a conversation to have with a clinician, not a conclusion.

Part of the broader category

Also called: Generalised bone demineralization

Generalized bone demineralization

Tracking symptoms like this for someone? Eleplan keeps symptoms, diagnoses, medications and every specialist in one plan.

Start free with Eleplan

This page uses the Human Phenotype Ontology (2026-06-23) — Human Phenotype Ontology Consortium, hpo.jax.org. Disease associations from Orphanet (INSERM), CC BY 4.0. Content is educational and is not medical advice.