Fundus hypopigmentation

What it means

Generalized or focal reduced pigmentation of the fundus, evaluated in the context of skin and hair color. Fundoscopy may reveal a low level pigment.

Fundus hypopigmentation is consistently observed in albinism. Pigmentation is also reduced with age in some individuals, high myopia, and in chronic inflammation, such as Harada disease. Ocular pigmentation is essential for normal vision, and persons with ocular albinism tend to have severely reduced visual acuity often associated with nystagmus, strabismus, and photophobia.

Rare diseases that can present with this9

The range is how often this sign appears among people diagnosed with each disease — it is not a probability of having any of them. Many of these signs also occur in common, non-rare conditions. A sign on this page is a conversation to have with a clinician, not a conclusion.

Part of the broader category

Also called: Decreased fundus pigmentation · Depigmented fundus · Hypopigmentation of the fundus