Rare diseases · Sign or symptom

Degeneration of anterior horn cells

HP:0002398

Rare diseases that can present with this4

The range is how often this sign appears among people diagnosed with each disease — it is not a probability of having any of them. Many of these signs also occur in common, non-rare conditions. A sign on this page is a conversation to have with a clinician, not a conclusion.

Part of the broader category

Also called: Anterior horn cell loss · Degeneration of alpha-motor neurons in anterior horn cells of the spinal cord · Degeneration of spinal cord anterior horn cells · Loss of spinal cord anterior horn cells · Progressive loss of anterior horn cells · Spinal cord anterior horn cell degeneration

Degeneration of anterior horn cells

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This page uses the Human Phenotype Ontology (2026-06-23) — Human Phenotype Ontology Consortium, hpo.jax.org. Disease associations from Orphanet (INSERM), CC BY 4.0. Content is educational and is not medical advice.