Rare diseases · Sign or symptom

Decreased level of heparin co-factor II

HP:0040226

What it means

An abnormality of coagulation related to a decreased concentration of heparin co-factor II

Requested and created by members of the BRIDGE consortium

Rare diseases that can present with this1

The range is how often this sign appears among people diagnosed with each disease — it is not a probability of having any of them. Many of these signs also occur in common, non-rare conditions. A sign on this page is a conversation to have with a clinician, not a conclusion.

Part of the broader category

Also called: Heparin co-factor II deficiency

Decreased level of heparin co-factor II

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This page uses the Human Phenotype Ontology (2026-06-23) — Human Phenotype Ontology Consortium, hpo.jax.org. Disease associations from Orphanet (INSERM), CC BY 4.0. Content is educational and is not medical advice.