Rare diseases · Sign or symptom
Decreased circulating specific pneumococcal antibody concentration
HP:0012476
What it means
The concentration in the blood circulation of specific immunoglobulins directed against pneumococci is below the lower limit of normal.
In general, this term is meant to be used for reduced specific antipneumococcal antibody concentration in the setting of normal overall immunoglobulin concentration.
Rare diseases that can present with this1
The range is how often this sign appears among people diagnosed with each disease — it is not a probability of having any of them. Many of these signs also occur in common, non-rare conditions. A sign on this page is a conversation to have with a clinician, not a conclusion.
Part of the broader category
Also called: Decreased specific pneumococcal antibody level · Low pneumococcal antibody titer · Specific pneumococcal antibody deficiency
Tracking symptoms like this for someone? Eleplan keeps symptoms, diagnoses, medications and every specialist in one plan.
Start free with EleplanThis page uses the Human Phenotype Ontology (2026-06-23) — Human Phenotype Ontology Consortium, hpo.jax.org. Disease associations from Orphanet (INSERM), CC BY 4.0. Content is educational and is not medical advice.