Rare diseases · Sign or symptom

Decreased circulating IgG1 concentration

HP:0032136

What it means

A reduction in immunoglobulin levels of the IgG1 subclass in the blood circulation.

Rare diseases that can present with this1

The range is how often this sign appears among people diagnosed with each disease — it is not a probability of having any of them. Many of these signs also occur in common, non-rare conditions. A sign on this page is a conversation to have with a clinician, not a conclusion.

Part of the broader category

Also called: Decreased circulating IgG1 level · Decreased IgG1 level in blood

Decreased circulating IgG1 concentration

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This page uses the Human Phenotype Ontology (2026-06-23) — Human Phenotype Ontology Consortium, hpo.jax.org. Disease associations from Orphanet (INSERM), CC BY 4.0. Content is educational and is not medical advice.