Rare diseases · Sign or symptom

Decreased beta-galactosidase activity

HP:0008166

What it means

Abnormally decreased rate of beta-galactosidase activity. Beta-galactosidase activity can be measured in leukocyte, fibroblast, or plasma.

Rare diseases that can present with this2

Very common80–99%

1

The range is how often this sign appears among people diagnosed with each disease — it is not a probability of having any of them. Many of these signs also occur in common, non-rare conditions. A sign on this page is a conversation to have with a clinician, not a conclusion.

Part of the broader category

Also called: Beta-galactosidase deficiency in fibroblasts and white blood cells · Beta-galactosidase-1 deficiency · Decreased beta galactosidase activity

Decreased beta-galactosidase activity

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This page uses the Human Phenotype Ontology (2026-06-23) — Human Phenotype Ontology Consortium, hpo.jax.org. Disease associations from Orphanet (INSERM), CC BY 4.0. Content is educational and is not medical advice.