Dalen-Fuchs nodules

What it means

Nodules (yellow-white subretinal pigment epithelium lesions) that form between Bruch membrane and the retinal pigment epithelium.

Dalen-Fuchs nodules may be observed with sympathetic ophthalmia, a rare, severe condition that typically presents as bilateral diffuse granulomatous uveitis secondary to trauma in one eye. Dalen-Fuchs nodules could be also observed in Harada disease.

Rare diseases that can present with this2

The range is how often this sign appears among people diagnosed with each disease — it is not a probability of having any of them. Many of these signs also occur in common, non-rare conditions. A sign on this page is a conversation to have with a clinician, not a conclusion.

Part of the broader category

Also called: Dalen Fuchs nodules