Rare diseases · Sign or symptom
Bruxism
Teeth grinding
HP:0003763
What it means
Bruxism is characterized by the grinding of the teeth including the clenching of the jaw and typically occur during sleep.
Rarely, bruxism can occur while the affected individual is awake, but this is less likely to result in the need for medical attention.
Rare diseases that can present with this17
Very common80–99%
3Common30–79%
6- ANK3-related intellectual disability-sleep disturbance syndrome
- CDKL5-deficiency disorder
- FOXG1 syndrome
- Neurodevelopmental disorder-craniofacial dysmorphism-cardiac defect-skeletal anomalies syndrome due to 9q21.3 microdeletion
- Neurodevelopmental disorder-craniofacial dysmorphism-cardiac defect-skeletal anomalies syndrome due to a point mutation
- Rett syndrome
Sometimes5–29%
8- 21q22.11q22.12microdeletion syndrome
- Choreoacanthocytosis
- Mowat-Wilson syndrome
- Mowat-Wilson syndrome due to a ZEB2 point mutation
- Mowat-Wilson syndrome due to monosomy 2q22
- MYT1L-related developmental delay-intellectual disability-obesity syndrome
- Neurodevelopmental disorder-craniofacial dysmorphism-cardiac defect-skeletal anomalies syndrome
- Oromandibular dystonia
The range is how often this sign appears among people diagnosed with each disease — it is not a probability of having any of them. Many of these signs also occur in common, non-rare conditions. A sign on this page is a conversation to have with a clinician, not a conclusion.
Part of the broader category
Also called: Grinding teeth during sleep
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Start free with EleplanThis page uses the Human Phenotype Ontology (2026-06-23) — Human Phenotype Ontology Consortium, hpo.jax.org. Disease associations from Orphanet (INSERM), CC BY 4.0. Content is educational and is not medical advice.