Rare diseases · Sign or symptom

Bilateral tonic-clonic seizure on awakening

Morning generalized tonic-clonic seizures

HP:0007193

What it means

Bilateral tonic-clonic seizure of either generalized or focal onset occurring on or soon after wakening (typically within 90 minutes of waking, regardless of the time of day).

Rare diseases that can present with this1

The range is how often this sign appears among people diagnosed with each disease — it is not a probability of having any of them. Many of these signs also occur in common, non-rare conditions. A sign on this page is a conversation to have with a clinician, not a conclusion.

Part of the broader category

Also called: Generalised tonic-clonic seizures on awakening · Generalized tonic-clonic seizures on awakening · Morning generalised tonic-clonic seizures

Bilateral tonic-clonic seizure on…

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This page uses the Human Phenotype Ontology (2026-06-23) — Human Phenotype Ontology Consortium, hpo.jax.org. Disease associations from Orphanet (INSERM), CC BY 4.0. Content is educational and is not medical advice.