Rare diseases · Sign or symptom
Atrial flutter
HP:0004749
What it means
A type of atrial arrhythmia characterized by atrial rates of between 240 and 400 beats per minute and some degree of atrioventricular node conduction block. Typically, the ventricular rate is half the atrial rate. In the EKG; atrial flutter waves are observed as sawtooth-like atrial activity. Pathophysiologically, atrial flutter is a form of atrial reentry in which there is a premature electrical impulse creates a self-propagating circuit.
Atrial flutter can lead to palpitations, fatigue, dyspnea, and chest pain. Atrial flutter can be paroxysmal or persistent.
Rare diseases that can present with this13
Sometimes5–29%
9- Absence of the pulmonary artery
- Atrial septal defect, ostium primum type
- Atrial septal defect, ostium secundum type
- Atrial septal defect, sinus venosus type
- Familial dilated cardiomyopathy with conduction defect due to LMNA mutation
- Interatrial communication
- Partial atrioventricular septal defect
- Tropical endomyocardial fibrosis
and 1 more in this range
The range is how often this sign appears among people diagnosed with each disease — it is not a probability of having any of them. Many of these signs also occur in common, non-rare conditions. A sign on this page is a conversation to have with a clinician, not a conclusion.
Part of the broader category
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Start free with EleplanThis page uses the Human Phenotype Ontology (2026-06-23) — Human Phenotype Ontology Consortium, hpo.jax.org. Disease associations from Orphanet (INSERM), CC BY 4.0. Content is educational and is not medical advice.