Anti-Glutamate Receptor delta2 antibody positivity

What it means

The presence of autoantibodies in the serum that react against glutamate receptor delta2.

Glutamate receptor delta2, a member of the glutamate receptor family, is predominantly expressed in cerebellar Purkinje cells and plays a crucial role in cerebellar functions. Anti-GluRdelta2 autoantibody has been detected in a patient with chronic cerebellitis.

Rare diseases that can present with this1

The range is how often this sign appears among people diagnosed with each disease — it is not a probability of having any of them. Many of these signs also occur in common, non-rare conditions. A sign on this page is a conversation to have with a clinician, not a conclusion.

Part of the broader category