Rare diseases · Sign or symptom
Abnormality of the philtrum
HP:0000288
What it means
An abnormality of the philtrum.
The paralabial region is the region surrounding the lips and includes the philtrum.
Rare diseases that can present with this13
Very common80–99%
5Common30–79%
6The range is how often this sign appears among people diagnosed with each disease — it is not a probability of having any of them. Many of these signs also occur in common, non-rare conditions. A sign on this page is a conversation to have with a clinician, not a conclusion.
Part of the broader category
Also called: Abnormal philtrum · Abnormality of the infranasal depression · Abnormality of the paralabial region
Tracking symptoms like this for someone? Eleplan keeps symptoms, diagnoses, medications and every specialist in one plan.
Start free with EleplanThis page uses the Human Phenotype Ontology (2026-06-23) — Human Phenotype Ontology Consortium, hpo.jax.org. Disease associations from Orphanet (INSERM), CC BY 4.0. Content is educational and is not medical advice.