Rare diseases · Sign or symptom

Abnormality of facial musculature

Abnormality of facial muscles

HP:0000301

What it means

An anomaly of a muscle that is innervated by the facial nerve (the seventh cranial nerve).

Facial muscles control facial expression and are innervated by the seventh cranial nerve. Facial muscles around the eye are responsible for eye blink and eyelid closure.

Rare diseases that can present with this2

Very common80–99%

1

Common30–79%

1

The range is how often this sign appears among people diagnosed with each disease — it is not a probability of having any of them. Many of these signs also occur in common, non-rare conditions. A sign on this page is a conversation to have with a clinician, not a conclusion.

Part of the broader category

Also called: Facial muscle issue

Abnormality of facial musculature

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This page uses the Human Phenotype Ontology (2026-06-23) — Human Phenotype Ontology Consortium, hpo.jax.org. Disease associations from Orphanet (INSERM), CC BY 4.0. Content is educational and is not medical advice.