Rare diseases · Sign or symptom

Abnormal vitamin B12 concentration

HP:0004341

What it means

The concentration of vitamin B12 (or one of its metabolites) in the blood circulation is outside the limits of normal.

Rare diseases that can present with this4

The range is how often this sign appears among people diagnosed with each disease — it is not a probability of having any of them. Many of these signs also occur in common, non-rare conditions. A sign on this page is a conversation to have with a clinician, not a conclusion.

Part of the broader category

Also called: Abnormal serum cobalamin level · Abnormal vitamin B12 level · Abnormality of the vitamin B12 metabolism

Abnormal vitamin B12 concentration

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This page uses the Human Phenotype Ontology (2026-06-23) — Human Phenotype Ontology Consortium, hpo.jax.org. Disease associations from Orphanet (INSERM), CC BY 4.0. Content is educational and is not medical advice.