Rare diseases · Sign or symptom
Abnormal transitional B cell proportion
HP:0030379
What it means
Abnormal increase or decrease of the transitional B cell subpopulation, commonly characterized as CD27-CD24hiCD38hi or CD27-IgMhiCD38hi, measured as percentage of total B cells in the blood, compared to a reference range for a given sex and age-group.
B cells originate from precursors in the bone marrow, and the first cells which migrate to the peripheral blood have been classified as transitional B cells.
Part of the broader category
Also called: Abnormal proportion of CD19+CD38+IgM+ cells · Abnormal proportion of transitional B cells
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Start free with EleplanThis page uses the Human Phenotype Ontology (2026-06-23) — Human Phenotype Ontology Consortium, hpo.jax.org. Disease associations from Orphanet (INSERM), CC BY 4.0. Content is educational and is not medical advice.