Rare diseases · Sign or symptom

Abnormal circulating bicarbonate concentration

HP:0032065

What it means

Any deviation from the normal concentration of bicarbonate, HCO3[-], in the circulation.

Bicarbonate represents the second largest category of anions in plasma. The measurement of bicarbonate also captures carbonate (CO3[-2]) ions, carbon dioxide in solution, and carbamino compounds but the latter represent a tiny fraction of the total measured amount.

Part of the broader category

Also called: Abnormal serum bicarbonate concentration · Abnormal serum HCO3 concentration

Abnormal circulating bicarbonate…

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This page uses the Human Phenotype Ontology (2026-06-23) — Human Phenotype Ontology Consortium, hpo.jax.org. Disease associations from Orphanet (INSERM), CC BY 4.0. Content is educational and is not medical advice.