Mixed neuroendocrine and…

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Mixed neuroendocrine and non-neuroendocrine neoplasm of pancreas

ORPHA:506112Disease

Also called MiNEN of pancreas · Pancreatic MiNEN · Pancreatic mixed neuroendocrine-nonneuroendocrine neoplasm

What it is

A rare neuroendocrine neoplasm of pancreas characterized by morphologically recognizable neuroendocrine and non-neuroendocrine components, each constituting at least 30% of the tumor volume. Based on histopathology, mixed ductal- and mixed acinar-neuroendocrine carcinomas are distinguished. Patients usually present with unspecific symptoms related to tumor growth and/or metastasis, although occurrence of Zollinger-Ellison syndrome has been reported. Resectability of the tumor is the most important prognostic factor.

Key facts

Inheritance
Not applicable
Classified as
Disease

ICD-10 codes

C25.9filed under a broader ICD-10 category — shared with 1 other rare disease

ICD-10 has no distinct code for most rare diseases, so many are filed under the nearest available one. A shared code identifies the group, not this disease — the ORPHAcode above is what identifies it.

Related health topics

Reached through the ICD-10 categories this disease is filed under, so these describe the broader group rather than this disease specifically.

Cross-references

MONDO 0044727MONDO 44727UMLS C5568577

Orphadata Science: Free access data from Orphanet. © INSERM 1999. Data version 2026-06-23. Available under CC BY 4.0. This is a reference, not medical advice.

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