High-grade neuroendocrine carcinoma of…

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High-grade neuroendocrine carcinoma of the cervix uteri

ORPHA:213777Disease

Also called High-grade neuroendocrine carcinoma of the uterine cervix · Poorly differentiated neuroendocrine carcinoma of the cervix uteri · Poorly differentiated neuroendocrine cervical carcinoma

What it is

High-grade neuroendocrine carcinoma of the cervix uteri is a rare, aggressive, primary cervical neoplasm, originating from neuroendocrine cells present in the lining epithelium of the cervix, characterized, macroscopically, by usually large lesions, sometimes with a barrel-shaped appearance. Patients often present with abnormal vaginal bleeding or discharge, pelvic/abdominal pain, post-coital spotting and/or dysuria, while symptoms related to carcinoid syndrome are not frequent.

Key facts

Age of onset
Adult, Elderly
Classified as
Disease

ICD-10 codes

C53.0ICD-10 uses a narrower term — shared with 10 other rare diseases
C53.1ICD-10 uses a narrower term — shared with 10 other rare diseases
C53.8ICD-10 uses a narrower term — shared with 10 other rare diseases

ICD-10 has no distinct code for most rare diseases, so many are filed under the nearest available one. A shared code identifies the group, not this disease — the ORPHAcode above is what identifies it.

Related health topics

Reached through the ICD-10 categories this disease is filed under, so these describe the broader group rather than this disease specifically.

Cross-references

MONDO 0016276UMLS C4751235

Orphadata Science: Free access data from Orphanet. © INSERM 1999. Data version 2026-06-23. Available under CC BY 4.0. This is a reference, not medical advice.

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