Epilepsy with auditory features

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Epilepsy with auditory features

ORPHA:101046Disease

Also called ADEAF · ADLTE · ADPEAF · Autosomal dominant epilepsy with auditory features · Autosomal dominant lateral temporal lobe epilepsy · EAF · Partial epilepsy with auditory aura · Partial epilepsy with auditory features

What it is

A rare, genetic, familial partial epilepsy disease characterized by focal seizures associated with prominent ictal auditory symptoms, and/or receptive aphasia, presenting in two or more family members and having a relatively benign evolution.

Key facts

Age of onset
Adolescent, Adult, Childhood
Inheritance
Autosomal dominant
Classified as
Disease

Signs and symptoms

These ranges are how often a sign appears across everyone diagnosed, not a prediction for one person — most people have some of these and not others. Orphanet also records findings that are specifically absent in this disease; those are in the data but not listed here.

Genes

LGI1Disease-causing germline mutation(s) (loss of function)
MICAL1Disease-causing germline mutation(s)
RELNDisease-causing germline mutation(s)

ICD-10 codes

G40.0filed under a broader ICD-10 category — shared with 8 other rare diseases

ICD-10 has no distinct code for most rare diseases, so many are filed under the nearest available one. A shared code identifies the group, not this disease — the ORPHAcode above is what identifies it.

Related health topics

Reached through the ICD-10 categories this disease is filed under, so these describe the broader group rather than this disease specifically.

Benefit programs to look at

Programs whose eligibility touches the same ICD-10 categories. Eligibility is decided by the administering agency, never by this page.

Cross-references

GARD 2257MESH C537297MONDO 0010898OMIM 600512OMIM 616436OMIM 616461UMLS C1838062

Orphadata Science: Free access data from Orphanet. © INSERM 1999. Data version 2026-06-23. Available under CC BY 4.0. This is a reference, not medical advice.

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