Diphtheria

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Diphtheria

ORPHA:1679Disease

What it is

A rare bacterial infectious disease characterized by an affliction of the upper respiratory tract mediated by the toxin of Corynebacterium diphtheriae. Symptoms include formation of an inflammatory pseudomembrane, fever, sore throat, headaches, coughing, dysphagia, dyspnea, and prominently swollen cervical lymph nodes. The disease may lead to respiratory failure and severe toxin-mediated damage of internal organs, including the heart and kidneys. A cutaneous form of diphtheria is more common in tropical climates and usually follows an indolent course.

Key facts

Prevalence
<1 / 1 000 000 (annual incidence, Europe)
Age of onset
All ages
Classified as
Disease

Prevalence figures describe populations, not individuals, and are often estimates from a single study. Where the figure is an incidence or a birth prevalence, it says so.

ICD-10 codes

A36.0ICD-10 uses a narrower term
A36.1ICD-10 uses a narrower term
A36.2ICD-10 uses a narrower term
A36.3ICD-10 uses a narrower term
A36.8ICD-10 uses a narrower term
A36.9ICD-10 uses a narrower term

Related health topics

Reached through the ICD-10 categories this disease is filed under, so these describe the broader group rather than this disease specifically.

Cross-references

GARD 1875MEDDRA 10013023MESH D004165MONDO 0005504UMLS C0012546

Orphadata Science: Free access data from Orphanet. © INSERM 1999. Data version 2026-06-23. Available under CC BY 4.0. This is a reference, not medical advice.

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