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Start free with EleplanAutoimmune hemolytic anemia, cold type
ORPHA:228312Clinical group
Also called cAHA · cAIHA · Cold AIHA
What it is
Cold autoimmune hemolytic anemia comprises two types of autoimmune hemolytic anemia (AIHA) defined by the presence of cold autoantibodies (autoantibodies which are active at temperatures below 30 °C): cold agglutinin disease (CAD), which is the more common, and paroxysmal cold hemoglobinuria (PCH).
Key facts
- Prevalence
- 1-9 / 100 000 (Europe)
- Age of onset
- All ages
- Inheritance
- Multigenic/multifactorial
- Classified as
- Clinical group
Prevalence figures describe populations, not individuals, and are often estimates from a single study. Where the figure is an incidence or a birth prevalence, it says so.
Cross-references
Orphadata Science: Free access data from Orphanet. © INSERM 1999. Data version 2026-06-23. Available under CC BY 4.0. This is a reference, not medical advice.
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