valproic acid 100 MG Oral Tablet
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valproic acid 100 MG Oral Tablet
100 MG · Oral Tablet · oral
A form of valproic acid →
valproic acid 100 MG Oral Tablet — Fatty acid derivatives. Strength, form, class, interactions & more.
Active ingredient
Classification
Fatty acid derivativesMood Stabilizer
Drug interactions
Valproic acid has several significant interactions with other drugs that can affect its clearance and efficacy.
- majorphenytoin — increased valproate clearance
- majorcarbamazepine — increased valproate clearance
- majorphenobarbital — increased valproate clearance
- majorprimidone — increased valproate clearance
- majorrifampin — increased valproate clearance
- moderatefelbamate — increased valproate peak concentration
- majorcarbapenem antibiotics — decreased valproate concentration leading to potential loss of seizure control
- moderateaspirin — decreased protein binding and metabolism of valproate
- majorestrogen-containing hormonal contraceptives — increased clearance of valproate leading to decreased concentration and potential increased seizure frequency
- moderatewarfarin — dosage adjustment may be necessary
- moderatezidovudine — dosage adjustment may be necessary
- moderateamitriptyline/nortriptyline — dosage adjustment may be necessary
- moderatepropofol — dosage adjustment may be necessary
- majortopiramate — hyperammonemia and encephalopathy
Source: RxNorm + openFDA + RxClass + FAERS · 2026
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