sevabertinib 10 MG Oral Tablet [Hyrnuo]
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sevabertinib 10 MG Oral Tablet [Hyrnuo]
10 MG · Oral Tablet · oral
A form of sevabertinib →
sevabertinib 10 MG Oral Tablet [Hyrnuo] — Human epidermal growth factor receptor 2 (HER2) tyrosine kinase inhibitors. Strength, form, class, interactions & more.
![sevabertinib 10 MG Oral Tablet [Hyrnuo]](https://dailymed.nlm.nih.gov/dailymed/image.cfm?setid=d7a11334-6e7a-445b-9a16-bdcd9acbe61f&name=hyrnuo-01.jpg)
Active ingredient
Classification
Human epidermal growth factor receptor 2 (HER2) tyrosine kinase inhibitors
Drug interactions
Sevabertinib has several interactions with CYP3A inhibitors, inducers, and substrates, as well as P-gp substrates.
- majorstrong CYP3A inhibitors — increased risk of HYRNUO-associated adverse reactions
- moderatemoderate CYP3A inhibitors — increased HYRNUO-associated adverse reactions
- majorstrong CYP3A inducers — decreased effectiveness of HYRNUO
- majormoderate CYP3A inducers — decreased effectiveness of HYRNUO
- majorCYP3A substrates — increased risk of serious adverse reactions
- moderateP-gp substrates — increased risk of adverse reactions
- moderateCYP1A1 substrates — increased risk of adverse reactions
Source: RxNorm + openFDA + RxClass + FAERS · 2026
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