sapropterin dihydrochloride 500 MG Powder for Oral Solution [Javygtor]
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sapropterin dihydrochloride 500 MG Powder for Oral Solution [Javygtor]
500 MG · Powder for Oral Solution · oral
A form of sapropterin dihydrochloride →
sapropterin dihydrochloride 500 MG Powder for Oral Solution [Javygtor] — Various alimentary tract and metabolism products. Strength, form, class, interactions & more.
![sapropterin dihydrochloride 500 MG Powder for Oral Solution [Javygtor]](https://dailymed.nlm.nih.gov/dailymed/image.cfm?setid=2e13a3b5-e4df-4d5c-9b26-02a7006a7c3e&name=sapropterin-dihydrochloride-1.jpg)
Active ingredient
Classification
Various alimentary tract and metabolism productsPhenylalanine Hydroxylase Activator
Drug interactions
Sapropterin dihydrochloride has several clinically important drug interactions that may affect its efficacy and safety.
- moderatelevodopa — may increase the availability of tyrosine, a precursor of levodopa
- moderateinhibitors of folate synthesis (e.g., methotrexate, valproic acid, phenobarbital, trimethoprim) — may decrease the bioavailability of endogenous BH4, potentially increasing Phe levels
- moderatePDE-5 inhibitors (e.g., sildenafil, vardenafil, tadalafil) — potential reduction in blood pressure due to combined vasorelaxation effects
Source: RxNorm + openFDA + RxClass + FAERS · 2026
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