sapropterin dihydrochloride 100 MG Oral Tablet
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sapropterin dihydrochloride 100 MG Oral Tablet
100 MG · Oral Tablet · oral
A form of sapropterin dihydrochloride →
sapropterin dihydrochloride 100 MG Oral Tablet — Various alimentary tract and metabolism products. Strength, form, class, interactions & more.
Active ingredient
Classification
Various alimentary tract and metabolism productsPhenylalanine Hydroxylase Activator
Drug interactions
Sapropterin dihydrochloride has several clinically important drug interactions that may affect its efficacy and safety.
- moderatelevodopa — may increase the availability of tyrosine, a precursor of levodopa
- moderateinhibitors of folate synthesis (e.g., methotrexate, valproic acid, phenobarbital, trimethoprim) — may decrease the bioavailability of endogenous BH4, potentially increasing Phe levels
- moderatePDE-5 inhibitors (e.g., sildenafil, vardenafil, tadalafil) — potential reduction in blood pressure due to combined vasorelaxation effects
Source: RxNorm + openFDA + RxClass + FAERS · 2026
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