piperacillin 400 MG/ML Injectable Solution

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Clinical drug

piperacillin 400 MG/ML Injectable Solution

400 MG/ML · Injectable Solution · injection

A form of piperacillin →

piperacillin 400 MG/ML Injectable Solution — Penicillins with extended spectrum. Strength, form, class, interactions & more.

piperacillin 400 MG/ML Injectable Solution

Active ingredient

Classification

Penicillins with extended spectrumPenicillin-class Antibacterial

Drug interactions

Piperacillin has several notable drug interactions that may affect its efficacy and safety.

  • majortobramycin — significantly reduced concentrations in hemodialysis patients
  • majorprobenecid — prolonged half-lives of piperacillin and tazobactam
  • majorvancomycin — increased incidence of acute kidney injury
  • moderateheparin and oral anticoagulants — coagulation parameters should be monitored more frequently
  • majorvecuronium — prolongation of neuromuscular blockade
  • moderatemethotrexate — reduced clearance of methotrexate

Real-world adverse events (FAERS)

Drug Ineffective3,072Off Label Use2,743Acute Kidney Injury2,315Pyrexia2,243Pneumonia1,501Diarrhoea1,427Thrombocytopenia1,263Sepsis1,240

Source: RxNorm + openFDA + RxClass + FAERS · 2026

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