piperacillin 400 MG/ML Injectable Solution
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piperacillin 400 MG/ML Injectable Solution
400 MG/ML · Injectable Solution · injection
A form of piperacillin →
piperacillin 400 MG/ML Injectable Solution — Penicillins with extended spectrum. Strength, form, class, interactions & more.

Active ingredient
Classification
Penicillins with extended spectrumPenicillin-class Antibacterial
Drug interactions
Piperacillin has several notable drug interactions that may affect its efficacy and safety.
- majortobramycin — significantly reduced concentrations in hemodialysis patients
- majorprobenecid — prolonged half-lives of piperacillin and tazobactam
- majorvancomycin — increased incidence of acute kidney injury
- moderateheparin and oral anticoagulants — coagulation parameters should be monitored more frequently
- majorvecuronium — prolongation of neuromuscular blockade
- moderatemethotrexate — reduced clearance of methotrexate
Real-world adverse events (FAERS)
Drug Ineffective3,072Off Label Use2,743Acute Kidney Injury2,315Pyrexia2,243Pneumonia1,501Diarrhoea1,427Thrombocytopenia1,263Sepsis1,240
Source: RxNorm + openFDA + RxClass + FAERS · 2026
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