pentazocine 50 MG Rectal Suppository
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pentazocine 50 MG Rectal Suppository
50 MG · Rectal Suppository · rectal
A form of pentazocine →
pentazocine 50 MG Rectal Suppository — Benzomorphan derivatives. Strength, form, class, interactions & more.

Active ingredient
Classification
Benzomorphan derivativesPartial Opioid Agonist/Antagonist
Drug interactions
Pentazocine has several significant drug interactions that can lead to serious adverse effects.
- majorbenzodiazepines and other CNS depressants — increased risk of hypotension, respiratory depression, profound sedation, coma, and death
- majorserotonergic drugs — risk of serotonin syndrome
- majormonoamine oxidase inhibitors (MAOIs) — CNS excitation and hypertension
- majormixed agonist/antagonist and partial agonist opioid analgesics — reduced analgesic effect and/or precipitate withdrawal symptoms
- majormuscle relaxants — enhanced neuromuscular blocking action and increased respiratory depression
- moderatediuretics — reduced efficacy of diuretics
- moderateanticholinergic drugs — increased risk of urinary retention and/or severe constipation
- minortobacco — reduced clinical effectiveness of pentazocine
Source: RxNorm + openFDA + RxClass + FAERS · 2026
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