nitrofurantoin, macrocrystals 100 MG Oral Capsule [Macrodantin]

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Clinical drug

nitrofurantoin, macrocrystals 100 MG Oral Capsule [Macrodantin]

100 MG · Oral Capsule · oral

A form of nitrofurantoin, macrocrystals →

nitrofurantoin, macrocrystals 100 MG Oral Capsule [Macrodantin] — Nitrofuran derivatives. Strength, form, class, interactions & more.

nitrofurantoin, macrocrystals 100 MG Oral Capsule [Macrodantin]

Active ingredient

nitrofurantoin, macrocrystals →

Classification

Nitrofuran derivativesNitrofuran Antibacterial

Drug interactions

Nitrofurantoin has known interactions with certain antacids and uricosuric drugs that can affect its absorption and efficacy.

  • moderateantacids containing magnesium trisilicate — reduces both the rate and extent of absorption
  • moderateprobenecid — inhibits renal tubular secretion of nitrofurantoin, increasing serum levels and potential toxicity
  • moderatesulfinpyrazone — inhibits renal tubular secretion of nitrofurantoin, increasing serum levels and potential toxicity

Real-world adverse events (FAERS)

Urinary Tract Infection356Drug Hypersensitivity266Fatigue230Nausea217Fall190Asthenia177Pain166Diarrhoea162

Source: RxNorm + openFDA + RxClass + FAERS · 2026

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