nirogacestat 100 MG Oral Tablet
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nirogacestat 100 MG Oral Tablet
100 MG · Oral Tablet · oral
A form of nirogacestat →
nirogacestat 100 MG Oral Tablet — Other antineoplastic agents. Strength, form, class, interactions & more.

Active ingredient
Classification
Other antineoplastic agentsGamma Secretase Inhibitor
Drug interactions
Nirogacestat has several drug interactions that may affect its efficacy and safety.
- majorstrong or moderate CYP3A inhibitors — increased risk of adverse reactions
- majorstrong or moderate CYP3A inducers — reduced effectiveness of nirogacestat
- majorproton pump inhibitors and H2-receptor antagonists — reduced effectiveness of nirogacestat
- majorCYP3A substrates — increased risk of adverse reactions related to these substrates
- majorCYP2C19 substrates — decreased efficacy of CYP2C19 substrates
Source: RxNorm + openFDA + RxClass + FAERS · 2026
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