neratinib 40 MG Oral Tablet [Nerlynx]
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neratinib 40 MG Oral Tablet [Nerlynx]
40 MG · Oral Tablet · oral
A form of neratinib →
neratinib 40 MG Oral Tablet [Nerlynx] — Human epidermal growth factor receptor 2 (HER2) tyrosine kinase inhibitors. Strength, form, class, interactions & more.
![neratinib 40 MG Oral Tablet [Nerlynx]](https://dailymed.nlm.nih.gov/dailymed/image.cfm?setid=d1e41dcf-e82a-47c2-a0ad-6c6eef621834&name=ner00-0019-01.jpg)
Active ingredient
Classification
Human epidermal growth factor receptor 2 (HER2) tyrosine kinase inhibitorsKinase Inhibitor
Drug interactions
Neratinib has several drug interactions that may affect its pharmacokinetics and toxicity.
- majorproton pump inhibitors — may decrease neratinib activity
- moderateH2-receptor antagonists — may decrease neratinib activity
- moderateantacids — may decrease neratinib activity
- majorstrong CYP3A4 inhibitors — may increase the risk of neratinib toxicity
- majorP-gp and moderate CYP3A4 dual inhibitors — may increase the risk of neratinib toxicity
- majorstrong or moderate CYP3A4 inducers — may reduce neratinib activity
- moderatecertain P-glycoprotein (P-gp) substrates — may increase the risk of adverse reactions
Source: RxNorm + openFDA + RxClass + FAERS · 2026
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