neratinib 40 MG Oral Tablet

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Clinical drug

neratinib 40 MG Oral Tablet

40 MG · Oral Tablet · oral

A form of neratinib →

neratinib 40 MG Oral Tablet — Human epidermal growth factor receptor 2 (HER2) tyrosine kinase inhibitors. Strength, form, class, interactions & more.

neratinib 40 MG Oral Tablet

Active ingredient

neratinib →

Classification

Human epidermal growth factor receptor 2 (HER2) tyrosine kinase inhibitorsKinase Inhibitor

Drug interactions

Neratinib has several drug interactions that may affect its pharmacokinetics and toxicity.

  • majorproton pump inhibitors — may decrease neratinib activity
  • moderateH2-receptor antagonists — may decrease neratinib activity
  • moderateantacids — may decrease neratinib activity
  • majorstrong CYP3A4 inhibitors — may increase the risk of neratinib toxicity
  • majorP-gp and moderate CYP3A4 dual inhibitors — may increase the risk of neratinib toxicity
  • majorstrong or moderate CYP3A4 inducers — may reduce neratinib activity
  • moderatecertain P-glycoprotein (P-gp) substrates — may increase the risk of adverse reactions

Source: RxNorm + openFDA + RxClass + FAERS · 2026

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